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KMID : 0362219920190010085
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Journal of The Korean Research Society for Dental Materials
1992 Volume.19 No. 1 p.85 ~ p.95
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A STUDY ON THE MUTAGENICITY OF SOME DENTAL BONDING RESINS AND DENTIN BONDING AGENTS BY MICRONUCLEUS TEST
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Abstract
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The purpose of this study was to evaluate the mutagenicity of bonding resins of dental composites and the dentin bonding agents. Eight bonding resins, six dentin bonding agents and distilled water (negative control) were administered orally and
cyclophosphamide (positive control) was administered intraperitoneally to the mice. The mice were killed by cervical dislocation at 24 hours after administration and the femurs were removed and dissected. The bone marrow cells were collected and
smeared
on glass slides and stained with haematoxylin-eosin staining method and were observed with light microscope (X450).
@ES The following results can be drawn:
@EN 1. The bonding resins of dental composites and the dentin bonding agents were tested in this study seemed tobe non-mutagenic.
2. The numbers of micronucleated polychromatic erythrocytes were similar both in the bonding resins of dental composites and the dentin bonding agents.
3. In the case of some products (AP, SC' and AA), the number of micronucleated polychromatic erythrocs was high beyond other products.
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KEYWORD
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